Preparation
Deslor Plus : Each extended release tablet contains Desloratadine INN 5 mg and Pseudoephedrine Hydrochloride USP 240 mg.
Indication
Deslor Plus is indicated for the relief of the nasal and non-nasal symptoms of allergic Rhinitis including nasal congestion.
Contraindication
Desloratadine and Pseudoephedrine combination is contraindicated in patients who are hypersensitive to this medication or to any of its ingredients or to Desloratadine or Loratadine. Due to its Pseudoephedrine component, it is contraindicated in patients with narrow-angle glaucoma, urinary retention, in patients receiving monoamine oxidase (MAO) inhibitor therapy or within fourteen (14) days of stopping such treatment, in patients with severe hypertension, severe coronary artery disease.
Dosage & Administration
Adults and children over 12 years of age
The recommended dose is Deslor Plus tablet once daily administered with or without a meal.Use should be avoided in patients with hepatic & renal impairment. It is not recommended for children under 12 years of age
Use in pregnancy and Lactation
Desloratadine and Pseudoephedrine combination may be used in pregnancy or during lactation only if the potential benefit justifies the potential risk to the fetus or nursing infant.
Side Effect
The common side effects are dry mouth, trouble sleeping, body aches or pain, hoarseness, weakness, restlessness, runny nose, sleepiness or unusual drowsiness, tender, swollen glands in neck, weight loss.
Precaution
Deslor Plus should be used with caution in patients with hypertension, diabetes mellitus, ischemic heart disease, increased intraocular pressure, hyperthyroidism or prostatic hypertrophy. Central nervous system stimulation with convulsions or cardiovascular collapse with accompanying hypotension may be produced by sympathomimetic amines.
Drug Interaction
No specific interaction studies have been conducted with Desloratadine and Pseudoephedrine combination. However, Pseudoephedrine reduces the antihypertensive effects of beta-adrenergic blocking agents, methyldopa, mecamylamine, reserpine, and veratrum alkaloids. Increased ectopic pacemaker activity can occur when pseudoephedrine is used concomitantly with digitalis.
Presentation
DeslorPlus tablet : Each box contains 3 X 10 tablets in blister strip.
