Preparation
Axet-125 Tablet: Each film coated tablet contains Cefuroxime Axetil USP equivalent to Cefuroxime 125 mg.
Axet-250 Tablet: Each film coated tablet contains Cefuroxime Axetil USP equivalent to Cefuroxime 250 mg.
Axet-500 Tablet: Each film coated tablet contains Cefuroxime Axetil USP equivalent to Cefuroxime 500 mg.
Axet Suspension: Each 5 ml suspension contains Cefuroxime Axetil USP equivalent to Cefuroxime 125 mg.
Axet 750 mg IV/IM Injection: Each vial contains Cefuroxime Sodium BP sterile powder for Injection equivalent to Cefuroxime 750 mg..
Therapeutic Class
Second Generation Cephalosporin Antibiotic
Indication
1.Upper and lower respiratory tract infections, such as acute and chronic bronchitis, pneumonia, sinusitis, otitis media, tonsillitis & pharyngitis.
2. Skin & soft tissue infections such as peritonitis, wound infections and impetigo.
3. Urinary tract infections such as pyelonephritis and cystitis.
4. Gonorrhoea.
5. Septicemia.
6. Meningitis.
7. Prophylaxis against infections in abdominal, pelvic, orthopedic, cardiac, pulmonary, oesophageal & vascular surgery.
Contraindication
Patients with known allergy to cephalosporins.
Side Effect
Cefuroxime treatment has been rarely associated with pseudomembranous colitis. Cefuroxime has been associated with nausea and vomiting in a small number of patients.
Precaution
Special care is indicated in patients who have experienced an allergic
reaction to penicillins or other beta-lactam antibiotics because there
is a risk of cross-sensitivity. As with all beta-lactam antibacterial
agents, serious and occasionally fatal hypersensitivity reactions have
been reported. In case of severe hypersensitivity reactions, treatment
with cefuroxime must be discontinued immediately and adequate emergency
measures must be initiated.
Drug Interaction
No interactions of this kind have been reported.
Presentation
Axet-125 Tablet: Box containing 2 x 10 tablets in Alu-Alu blister pack.
Axet-250 Tablet: Box containing 2 x 10 tablets in Alu-Alu blister pack.
Axet-500 Tablet: Box containing 3 x 4 tablets in Alu-Alu blister pack.
Axet Suspension: After reconstitution, each bottle contains 70 ml Suspension.
Axet 250 mg IV/IM Injection: Combipack of 1 vial of 250 mg Cefuroxime as sterile Cefuroxime Sodium BP & 1 ampoule of 5 ml Water for Injection BP & also a 5 ml syringe in a carton.
Axet 750 mg IV/IM Injection: Combipack of 1 vial of 750 mg Cefuroxime as sterile Cefuroxime Sodium BP & 1 ampoule of 10 ml Water for Injection BP & also a 10 ml syringe in a carton.