Each tablet contains Tamsulosin Hydrochloride USP 0.4 mg.
Drug For Urinary Retention
Tamlosin is used in Benign Prostatic Hyperplasia. It relaxes smooth muscle in benign prostatic hyperplasia producing an increase in urinary flow-rate and an improvement in obstructive symptoms.
Tamsulosin should be avoided in-patients with a history of orthostatic hypotension and micturition syncope.
Dosage & Administration
Tamlosin tablet once daily is recommended as the dose for the treatment of the signs and symptoms of BPH. It should be administered approximately one-half hour following the same meal each day. For those patients who fail to respond to the 0.4 mg dose after two to four weeks of dosing, the dose of Tamlosin tablet can be increased to 0.8 mg once daily. If Tamlosin administration is discontinued or interrupted for several days at either the 0.4 mg or 0.8 mg dose, therapy should be started again with the 0.4 mg once daily dose.
The following adverse reactions have been reported during the use of Tamsulosin: dizziness, abnormal ejaculation, and less frequently (1-2%) headache, asthenia, postural hypotension, palpitations etc.
Since Tamsulosin reduces blood pressure, patients receiving antihypertensive treatment may require reduced dosage and specialist supervision. Caution may be required in patients with hepatic impairment and severe renal impairment.
Tamsulosin Hydrochloride tablet are not indicated for use in women.
No interactions have been seen when Tamsulosin was given concomitantly with either atenolol, enalapril, nifedipine or theophylline. Concomitant cimetidine brings about a rise in plasma levels of Tamsulosin, and frusemide a fall, but as levels remain within the normal range dose change may not be required. There is a risk of enhanced hypotensive effect when given concurrently with drugs which may reduce blood pressure, including anaesthetic agents and other a1 adrenoceptor antagonists.