Boncare 150 mg Tablet: Each film-coated tablet contains Ibandronate Sodium INN equivalent to Ibandronic Acid INN 150 mg.
Bone Modulating Agent
Boncare is indicated for the: - Prevention & treatment of osteoporosis in women (specially postmenopausal). - Prevention & treatment of osteoporosis in men.
Important Limitations of Use: The optimal duration of use has not been determined. The safety and effectiveness of Boncare tablets for the treatment of osteoporosis are based on clinical data. All patients on bisphosphonate therapy should have the need for continued therapy re-evaluated on a periodic basis. Patients at low-risk for fracture should be considered for drug discontinuation after 3 to 5 years of use. Patients who discontinue therapy should have their risk for fracture re-evaluated periodically.
Boncare is contraindicated in patients with - Known hypersensitivity to Ibandronic Acid or to any of its excipients. - Uncorrected hypocalcemia. - Inability to stand or sit upright for at least 60 minutes.
Dosage & Administration
The recommended dose of Boncare for the treatment and prevention of osteoporosis is one 150 mg tablet once-a-month.
Gastrointestinal adverse reactions: Patients with a previous history of gastrointestinal disease including patients with peptic ulcer without recent bleeding or hospitalisation and patients with dyspepsia or reflux controlled by medication were included in the once monthly treatment study. Osteonecrosis of jaw: Osteonecrosis of the jaw has been reported in patients treated by bisphosphonates. The majority of the reports refer to cancer patients, but such cases have also been reported in patients treated for osteoporosis.
- Hypocalcemia and other disturbances of bone and mineral metabolism should be effectively treated before starting Boncare therapy. - Adequate intake of Calcium and Vitamin-D is important in all patients. - Patients should also pay particular attention to and be able to comply with the dosing instructions to minimize the risk of gastrointestinal side effects.
It is likely that products containing Calcium and other multivalent cations (such as Aluminium, Magnesium, Iron) including milk, food and antacids are likely to interfere with absorption of Ibandronate. Therefore, patients must wait 60 minutes after taking Boncare before taking other oral medications.