Preparation
Tendonil® Capsule: Each capsule contains Acemetacin BP 60 mg.
Indication
Pain & inflammation associated with musculoskeletal & joint disorders. Such as: Rheumatoid arthritis, Osteoarthritis, Low back pain. and Pain after an operation.
Contraindication
Tendonil® is contraindicated to known hypersensitivity to Acemetacin or Indomethacin; peptic ulcer; safety in children is not established.
Dosage & Administration
The recommended starting dose is 120 mg/day in divided doses, increasing to 180 mg/day in divided doses, depending on patient response. For the treatment of elderly patients, adjustment of dosage is not normally required. However, NSAIDs should be used with particular care in older patients who may be more prone to adverse reactions. Tendonil® should be taken with food, milk or an antacid to reduce the possibility of gastro-intestinal disturbance.
Side Effect
Common side effects include anorexia, nausea, vomiting, diarrhea and constipation, peptic ulcer, headache, dizziness & vertigo.
Precaution
Caution should be taken in elderly people, history of disorders affecting the stomach or intestines, inflammatory bowel disease such as Crohn's disease or ulcerative colitis, kidney disease, liver disease, heart failure.
Drug Interaction
Tendonil® reduces the antihypertensive effect of β-blockers. Increased risk of convulsion when used with Quinolone. Concurrent use with Aspirin, NSAIDs or Corticosteroids may increase risk of GI bleeding. Increased risk of Methotrexate toxicity when used together.
Presentation
Each box contains 3 x 10's capsules in blister pack.
Use Children
The safety in children and adolescents is not established.
Use Pregnancy Lactation
The safety of this medicine in human pregnancy and lactation has not been established.Therefore, use of this drug during pregnancy and lactation period is not recommended.
Storage
Store in a cool dry place, protected from light. Store below 25 °C. Keep all medicine out of the reach of children.
