Management of hypertension, angina pectoris ,
cardiac arrhythmias, treatment of myocardial
infarction, early and late intervention after
myocardial infarction.

Hypertension:
The initial dose is 50 mg once daily, either alone or
added to diuretic therapy. If an optimal response is
not achieved, the dose should be increased to 100
mg daily. Increasing the dosage beyond 100 mg a
day is unlikely to produce any further benefit.
Angina Pectoris:
The Initial dose is 50 mg/day. If an optimal
response is not achieved within one week, the dose
should be increased to 100 mg/day. Some patient
may require 200 mg/day for optimal effect.
Acute Myocardial Infarction:
IV: Early intervention within 12 hours, 5 mg over 5
minutes followed by another 5 mg IV injection 10
minutes later.
Oral: 50 mg tablet 10 minutes after the last IV dose
followed by another 50 mg dose 12 hours later.
Thereafter, 100 mg once daily or 50 mg twice dally
should be administered for a further 6 to 9 days or
until discharge from the hospital.
Cardiac Arrhythmias:
In patients with proximal supraventricular
tachycardia, intravenous Atenolol (Lopres) 0.15
mg/kg over 20 minutes, followed by 50-100 mg per
day orally as prophylactic treatment.
Contra-lndlcatlons
Second or third degree heart block, untreated heart
failure, cardiogenic shock.

Atenolol (Lopres) should be used with caution in
pregnant and lactating mother.

Reserpine: Concomitant administration of Atenolol
(Lopres) with reserpine may increase the incidence
of hypotension and bradycardia as compared with
Atenolol (Lopres) alone because of reserpine\'s
catecholamine depleting activity. Clonldine: Betablockers
may exacerbate the rebound hypertension,
which can follow the withdrawal of clonidlne. If
clonidlne is replaced by beta-blocker therapy, the
introduction of beta-blockers should be delayed for
several days after clonldine administration has
stopped.

In therapeutic dosage Atenolol (Lopres) usually is
well tolerated and has a low incidence of adverse
effects. Side effects include coldness of extremities,
gastrointestinal discomfort, skin rash and reduced
heart rate.

Each box contains 10X10 tablets in blister strips.

Lopres 50 Tablet : Each tablet contains Atenolol BP
50 mg.

Store below 35\'C, protected from light and
moisture.