Management of hypertension, angina pectoris , cardiac arrhythmias, treatment of myocardial infarction, early and late intervention after myocardial infarction.
Hypertension: The initial dose is 50 mg once daily, either alone or added to diuretic therapy. If an optimal response is not achieved, the dose should be increased to 100 mg daily. Increasing the dosage beyond 100 mg a day is unlikely to produce any further benefit. Angina Pectoris: The Initial dose is 50 mg/day. If an optimal response is not achieved within one week, the dose should be increased to 100 mg/day. Some patient may require 200 mg/day for optimal effect. Acute Myocardial Infarction: IV: Early intervention within 12 hours, 5 mg over 5 minutes followed by another 5 mg IV injection 10 minutes later. Oral: 50 mg tablet 10 minutes after the last IV dose followed by another 50 mg dose 12 hours later. Thereafter, 100 mg once daily or 50 mg twice dally should be administered for a further 6 to 9 days or until discharge from the hospital. Cardiac Arrhythmias: In patients with proximal supraventricular tachycardia, intravenous Atenolol (Lopres) 0.15 mg/kg over 20 minutes, followed by 50-100 mg per day orally as prophylactic treatment. Contra-lndlcatlons Second or third degree heart block, untreated heart failure, cardiogenic shock.
Atenolol (Lopres) should be used with caution in pregnant and lactating mother.
Reserpine: Concomitant administration of Atenolol (Lopres) with reserpine may increase the incidence of hypotension and bradycardia as compared with Atenolol (Lopres) alone because of reserpine\'s catecholamine depleting activity. Clonldine: Betablockers may exacerbate the rebound hypertension, which can follow the withdrawal of clonidlne. If clonidlne is replaced by beta-blocker therapy, the introduction of beta-blockers should be delayed for several days after clonldine administration has stopped.
In therapeutic dosage Atenolol (Lopres) usually is well tolerated and has a low incidence of adverse effects. Side effects include coldness of extremities, gastrointestinal discomfort, skin rash and reduced heart rate.
Each box contains 10X10 tablets in blister strips.
Lopres 50 Tablet : Each tablet contains Atenolol BP 50 mg.
Store below 35\'C, protected from light and moisture.