Iron is one of the most abundant metals in the universe. It is also one of the most useful component in biochemical functions. In the human body, Iron is present in all cells and has several vital functions- as a career of oxygen to the tissues from the lungs in the form of hemoglobin (Hb), as a facilitator of oxygen use and storage in the muscles as myoglobin, as a transport medium for electrons within the cells in the form of cytochromes, and as an integral part of enzyme reactions in various tissues . Carbonyl Iron is the safest form of supplemental iron available, with reduced risk of harm in the event of an accidental overdose. Additionally, carbonyl iron is gentle on the stomach. Zinc deficient cells fail to divide and differentiate, with consequent growth impairment, tissues with a high rate of cellular turnover including skin, gastrointestinal mucosa, chondrocytes, spermatogonia, and thymocyte are affected. Systems influenced by Zinc include the reproductive, neurological, immunological, dermatological and gastrointestinal system. Folic acid is a member of vitamin B group. Folic acid is reduced in the body to tetrahydrofolate, which is a co-enzyme for various metabolic processes including the synthesis of purine and pyrimidine nucleotides, and hence in the synthesis of DNA; it is also involved in some amino acid conversions, and in the formation and utilization of formate.
Dosage & Administration
It is indicated for the treatment and prophylaxis of Iron, Folic acid & Zinc deficiency, specially during pregnancy and lactation.
One capsule daily throughout the pregnancy and lactation or as directed by the physician.
Hypersensitivity to any components of the product
Folic acid in doses above 0.1 mg daily may obscure pernicious anemia, in that hematologic remission can occur while neurological menifestations remain progressive. Care should be taken in patients who may develop iron overload, such as those with hemochromatosis, hemolytic anemia or red cell aplasia.
Use Pregnancy Lactation
Use of any drug during the first trimester of pregnancy should be avoided if possible. Thus administration of iron during the first trimester requires definite evidence of iron deficiency. Prophylaxis of iron deficiency, where inadequate diet calls for supplementary Zinc and Folic acid, is justified during the remainder of pregnancy.
Iron and Zinc chelates with tetracyclines and absorption of all three agents may be impaired. The absorption of iron may also be reduced by Antacid and Penicillin.
Black discoloration of stool is usual during iron therapy. Nausea and other symptoms of gastrointestinal irritation such as anorexia, vomiting, discomfort may occur.
Each pellet capsule contains Carbonyl Iron Ph. Grade 51 mg
(Equivalent to 50 mg elemental Iron), Folic Acid BP 0.5 mg & Zinc
Sulphate BP 61.8 mg (Equivalent to 22.5 mg elemental Zinc).